Zn(II) complex for selective and rapid scission of protein backbone.

نویسندگان

  • Morio Yashiro
  • Yukiko Kawakami
  • Jun-ichi Taya
  • Suguru Arai
  • Yuki Fujii
چکیده

A ZnII complex with an aldehyde group hydrolyzed porcine pancreatic elastase under mild conditions, pH 8.0, 50 degrees C, by the Schiff base formation between the ZnII complex and the NH2 group in the protein, suggesting that a ZnII compound can be active toward peptide hydrolysis when it strongly binds to the substrate.

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عنوان ژورنال:
  • Chemical communications

دوره 12  شماره 

صفحات  -

تاریخ انتشار 2009